Rhesus macaques self-curing from a schistosome infection can display complete immunity to challenge

Autor: Murilo Sena Amaral, Daisy Woellner Santos, Adriana S. A. Pereira, Ana Carolina Tahira, João V. M. Malvezzi, Patrícia Aoki Miyasato, Rafaela de Paula Freitas, Jorge Kalil, Elisa M. Tjon Kon Fat, Claudia J. de Dood, Paul L. A. M. Corstjens, Govert J. van Dam, Eliana Nakano, Simone de Oliveira Castro, Vânia Gomes de Moura Mattaraia, Ronaldo de Carvalho Augusto, Christoph Grunau, R. Alan Wilson, Sergio Verjovski-Almeida
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-021-26497-0
Popis: To date there is only one single drug with modest efficacy and no vaccine available to protect from schistosomiasis. Here, Amaral et al. characterize the self-cure process of rhesus macaques following primary infection and secondary challenge with Schistosoma mansoni to inform future vaccine development studies.
Databáze: Directory of Open Access Journals