Comparison of Esmolol to Nitroglycerine in Controlling Hypotension during Nasal Surgery
| Autor: | Ayla Guney, Fatma Nur Kaya, Belgin Yavascaoglu, Alp Gurbet, Nazan Has Selmi, Sener Kaya, Oya Kutlay |
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| Jazyk: | angličtina |
| Rok vydání: | 2012 |
| Předmět: | |
| Zdroj: | Eurasian Journal of Medicine, Vol 44, Iss 2, Pp 99-105 (2012) |
| Druh dokumentu: | article |
| ISSN: | 1308-8734 1308-8742 |
| Popis: | Objective: The aim of this study was to compare esmolol to nitroglycerine in terms of effectiveness in controlling hypotension during nasal surgery. Materials and Methods: After approval by our institutional Ethics Committee, 40 patients were recruited and randomized into two drug groups: esmolol (Group E) and nitroglycerine (Group N). In group E, a bolus dose of 500 μg/kg esmolol was administered over 30 sec followed by continuous administration at a dose of 25-300 μg/kg/min to maintain systolic arterial pressure at 80 mmHg. In group N, nitroglycerine was administered at a dose of 0.5-2 μg/kg/min. Results: During the hypotensive period, systolic arterial pressure, diastolic arterial pressure, mean arterial pressure, and heart rate were decreased 24%, 33%, 27% and 35%, respectively, in group E (p |
| Databáze: | Directory of Open Access Journals |
| Externí odkaz: |
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