| Autor: |
Romina Soledad Coloccini, Dario Dilernia, Yanina Ghiglione, Gabriela Turk, Natalia Laufer, Andrea Rubio, María Eugenia Socías, María Inés Figueroa, Omar Sued, Pedro Cahn, Horacio Salomón, Andrea Mangano, María Ángeles Pando |
| Jazyk: |
angličtina |
| Rok vydání: |
2014 |
| Předmět: |
|
| Zdroj: |
PLoS ONE, Vol 9, Iss 11, p e113146 (2014) |
| Druh dokumentu: |
article |
| ISSN: |
1932-6203 |
| DOI: |
10.1371/journal.pone.0113146 |
| Popis: |
Variants in HIV-coreceptor C-C chemokine receptor type 5 (CCR5) and Human leukocyte antigen (HLA) genes are the most important host genetic factors associated with HIV infection and disease progression. Our aim was to analyze the association of these genetic factors in the presence of clinical symptoms during Primary HIV Infection (PHI) and disease progression within the first year.Seventy subjects diagnosed during PHI were studied (55 symptomatic and 15 asymptomatic). Viral load (VL) and CD4 T-cell count were evaluated. HIV progression was defined by presence of B or C events and/or CD4 T-cell counts |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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