Ramping dynamics and theta oscillations reflect dissociable signatures during rule-guided human behavior

Autor: Jan Weber, Anne-Kristin Solbakk, Alejandro O. Blenkmann, Anais Llorens, Ingrid Funderud, Sabine Leske, Pål Gunnar Larsson, Jugoslav Ivanovic, Robert T. Knight, Tor Endestad, Randolph F. Helfrich
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Druh dokumentu: article
ISSN: 2041-1723
35870273
DOI: 10.1038/s41467-023-44571-7
Popis: Abstract Contextual cues and prior evidence guide human goal-directed behavior. The neurophysiological mechanisms that implement contextual priors to guide subsequent actions in the human brain remain unclear. Using intracranial electroencephalography (iEEG), we demonstrate that increasing uncertainty introduces a shift from a purely oscillatory to a mixed processing regime with an additional ramping component. Oscillatory and ramping dynamics reflect dissociable signatures, which likely differentially contribute to the encoding and transfer of different cognitive variables in a cue-guided motor task. The results support the idea that prefrontal activity encodes rules and ensuing actions in distinct coding subspaces, while theta oscillations synchronize the prefrontal-motor network, possibly to guide action execution. Collectively, our results reveal how two key features of large-scale neural population activity, namely continuous ramping dynamics and oscillatory synchrony, jointly support rule-guided human behavior.
Databáze: Directory of Open Access Journals
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