Research Progress of Glucose Metabolism Reprogramming in Basic Research and Clinical Diagnosis and Treatment of Tumor

Autor: JIANG Yuan, CHEN Ya, XIE Yangyang, HUANG Xinyu, ZHAO Jian, LIANG Beibei
Jazyk: čínština
Rok vydání: 2021
Předmět:
Zdroj: Zhongliu Fangzhi Yanjiu, Vol 48, Iss 6, Pp 635-641 (2021)
Druh dokumentu: article
ISSN: 1000-8578
DOI: 10.3971/j.issn.1000-8578.2021.20.1425
Popis: Tumors provide materials and energy for themselves through glucose metabolic reprogramming to meet the needs of their rapid growth. Studies have shown that a variety of metabolic enzymes and signal molecules involved in glucose metabolism play an important role in tumorigenesis and development, and are considered to be important targets for the diagnosis and treatment of malignant tumors. The detection technology based on tumor glucose metabolism has been widely used in basic research and clinical diagnosis and treatment of tumor. This paper summarizes the characteristics, driving factors and key regulatory targets of tumor glucose metabolism, and the detection techniques and functions of tumor glucose metabolism from the aspects of basic medical research and clinical diagnosis and treatment.
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