Polycarbonate-based ultra-pH sensitive nanoparticles improve therapeutic window
| Autor: | Xu Wang, Jonathan Wilhelm, Wei Li, Suxin Li, Zhaohui Wang, Gang Huang, Jian Wang, Houliang Tang, Sina Khorsandi, Zhichen Sun, Bret Evers, Jinming Gao |
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| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: | |
| Zdroj: | Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020) |
| Druh dokumentu: | article |
| ISSN: | 2041-1723 77848918 |
| DOI: | 10.1038/s41467-020-19651-7 |
| Popis: | Stimuli-responsive nanomaterials offer the opportunity to exploit nanoscale cooperativity to improve the precision of diagnostic or therapeutic outcomes. Here, the authors report the design, synthesis and characterization of a series of degradable ultra-pH sensitive polymers that amplify small acidic pH changes to efficacious therapeutic outputs. |
| Databáze: | Directory of Open Access Journals |
| Externí odkaz: |
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