(R)-(+)-2-{[(3-Methyl-4-nitropyridin-2-yl)methyl]sulfinyl}-1H-benzimidazoleDRL-IPD Communication No. IPDO-IPM-00262.
| Autor: | Manne Naga Raju, Neelam Uday Kumar, Naveenkumar Kolla, Rakeshwar Bandichhor, Peddy Vishweshwar |
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| Jazyk: | angličtina |
| Rok vydání: | 2011 |
| Předmět: | |
| Zdroj: | Acta Crystallographica Section E, Vol 67, Iss 8, Pp o2190-o2190 (2011) |
| Druh dokumentu: | article |
| ISSN: | 16005368 1600-5368 |
| DOI: | 10.1107/S1600536811029990 |
| Popis: | The title compound, C14H12N4O3S, is an intermediate of Dexlansoprazole, a proton pump inhibitor (PPI) mainly developed for anti-ulcer activity. The absolute configuration of the title compound was determined as R. The crystal structure reveals that the molecules form chains along the b axis through N—H...N and C—H...O hydrogen-bonded dimers. These chains are connected via weak C—H...O hydrogen bonds. |
| Databáze: | Directory of Open Access Journals |
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