| Autor: |
Sheikh Asfandyar, Alvi Arsalan, Aslam Hafiz, Haseeb Abdul |
| Jazyk: |
angličtina |
| Rok vydání: |
2012 |
| Předmět: |
|
| Zdroj: |
Infectious Agents and Cancer, Vol 7, Iss 1, p 29 (2012) |
| Druh dokumentu: |
article |
| ISSN: |
1750-9378 |
| DOI: |
10.1186/1750-9378-7-29 |
| Popis: |
Abstract The Hedgehog (Hh) proteins comprise a group of secreted proteins that regulate cell growth, differentiation and survival. Inappropriate activation of the Hh signaling pathway has been implicated in the development of a variety of cancers. Hedgehog pathway inhibitors are a relatively new class of therapeutic agents that act by targeting the proteins involved in the regulation of Hh pathway (PTCH, SMO and Gli). Together, they serve as exciting new prospects, with a bright future, both alone or as an adjuvant to the more traditional anti-cancer drugs. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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