CIC-DUX4 sarcoma: A case report and review of the literature

Autor: Chang-Hung Liao, Yi-Jen Peng, Yi-Chih Hsu, Ping-Ying Chang
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Journal of Medical Sciences, Vol 42, Iss 5, Pp 249-252 (2022)
Druh dokumentu: article
ISSN: 1011-4564
DOI: 10.4103/jmedsci.jmedsci_241_21
Popis: CIC-DUX4 sarcoma is highly aggressive and rapidly develops lethal metastatic disease and chemoresistance. Its histology is similar to that of Ewing sarcoma and other small round cell sarcomas. Correlation with clinical data, radiological findings, pathological results (including immunohistochemistry and fluorescence in situ hybridization), and/or molecular techniques is necessary. We present the case of a 44-year-old woman who was initially diagnosed as having high-grade undifferentiated round cell sarcoma confirmed to be a CIC-DUX sarcoma by next-generation sequencing.
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