COVID-19 Death and BCG Vaccination Programs Worldwide

Autor: Feras J. Jirjees, Yahya H. Dallal Bashi, Hala J. Al-Obaidi
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Tuberculosis and Respiratory Diseases, Vol 84, Iss 1, Pp 13-21 (2021)
Druh dokumentu: article
ISSN: 1738-3536
2005-6184
DOI: 10.4046/trd.2020.0063
Popis: Several clinical trials are being conducted worldwide to investigate the protective effect of the bacillus Calmette-Guérin (BCG) vaccine against death in healthcare providers who are working directly with coronavirus disease 2019 (COVID-19) patients. Clinical studies suggested that certain live vaccines, particularly the BCG vaccine, could reduce the mortality due to other diseases caused by non-targeted pathogens, most probably through the nonspecific effects (heterologous effects). By the end of May 2020, the available information on the COVID-19 pandemic indicated the great effect of the BCG vaccine in reducing the number of COVID-19 death cases. The occurrence of death due to COVID-19 was found to be 21-fold lower in countries with a national BCG vaccination policy than in countries without such a policy, based on the medians of COVID-19 death case per 1 million of the population in these two groups of countries (p
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