Potensi Senyawa Bioaktif Ekstrak Kasar Bakteri Simbion Spons sebagai Anthelmintika : Sebuah Uji Pendahuluan
| Autor: | Muhammad Reza Faisal, Mujizat Kawaroe, Fadjar Satria |
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| Jazyk: | English<br />Indonesian |
| Rok vydání: | 2014 |
| Předmět: | |
| Zdroj: | Omni-Akuatika, Vol 10, Iss 2 (2014) |
| Druh dokumentu: | article |
| ISSN: | 1858-3873 2476-9347 |
| DOI: | 10.20884/1.oa.2014.10.2.23 |
| Popis: | This study aims to observe the bacterial symbionts of sponge and determine chemical compounds profile in the crude extract of bacterial isolates then to determine the lethal toxicity values (LC50-24 hours) as a preliminary anthelmintic test. The method consisted of the identification of gram staining, organic solvent extraction, phytochemical screening and toxicity assay by the Artemia salina LC50-24 hours. The concentration used consisted of 10 µg / ml; 100 µg / ml; 250 µg / ml; 500 µg / ml. Results showed isolate SC12 (2) C and S1-2 (1) belonging to the gram-positive where the bioactive compounds i.e. flavonoids and triterpenoids obtained from the crude extract were predominant. The minimum concentrations from toxicity tests were 35.11 µg/ml for isolate SC12(2)C and 41.2 µg/ml for S1-2 (1). The crude extract of both isolates showed potential as a anthelmintic compound with concentration LC50-24 hours |
| Databáze: | Directory of Open Access Journals |
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