The use of non-steroidal anti-inflammatory drugs (NSAIDs) in COVID-19

Autor: Pamela Kushner, Bill H. McCarberg, Laurent Grange, Anton Kolosov, Anela Lihic Haveric, Vincent Zucal, Richard Petruschke, Stephane Bissonnette
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: npj Primary Care Respiratory Medicine, Vol 32, Iss 1, Pp 1-10 (2022)
Druh dokumentu: article
ISSN: 2055-1010
DOI: 10.1038/s41533-022-00300-z
Popis: Abstract Early in the COVID-19 pandemic, anecdotal reports emerged suggesting non-steroidal anti-inflammatory drugs (NSAIDs) may increase susceptibility to infection and adversely impact clinical outcomes. This narrative literature review (March 2020–July 2021) attempted to clarify the relationship between NSAID use and COVID-19 outcomes related to disease susceptibility or severity. Twenty-four relevant publications (covering 25 studies) reporting original research data were identified; all were observational cohort studies, and eight were described as retrospective. Overall, these studies are consistent in showing that NSAIDs neither increase the likelihood of SARS-CoV-2 infection nor worsen outcomes in patients with COVID-19. This is reflected in current recommendations from major public health authorities across the world, which support NSAID use for analgesic or antipyretic treatment during COVID-19. Thus, there is no basis on which to restrict or prohibit use of these drugs by consumers or patients to manage their health conditions and symptoms during the pandemic.
Databáze: Directory of Open Access Journals