Efficacy of Topical Brinzolamide Treatment in Posterior Microphthalmos- Related Macular Cystoid Lesions: A Case Series

Autor: Ceren Durmaz Engin, Umut Baran Ekinci, Alper Selver, Ali Osman Saatci
Jazyk: English<br />Turkish
Rok vydání: 2020
Předmět:
Zdroj: Türk Oftalmoloji Dergisi, Vol 50, Iss 1, Pp 44-49 (2020)
Druh dokumentu: article
ISSN: 1300-0659
2147-2661
DOI: 10.4274/tjo.galenos.2019.40504
Popis: The aim of this study was to report the outcome of topical brinzolamide 1% treatment on macular cystoid lesions resembling retinoschisis in 4 patients diagnosed with posterior microphthalmia. The medical records of 4 patients with a clinical diagnosis of posterior microphthalmia who had started topical brinzolamide 1% treatment were reviewed. Visual acuity, central foveal thickness, and cystoid lesion area percentage were used to evaluate treatment response. In the follow-up, there was a decrease in central foveal thicknesses and cystoid lesion area percentages in both eyes of 3 of the patients. However, 1 patient showed increases in both parameters. Visual acuity remained stable in 5 eyes and increased in 3 eyes. Topical brinzolamide treatment may have some positive effects on macular cystoid lesions in selected cases.
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