Serum levels of irisin and nesfatin-1 in multiple sclerosis

Autor:	Mustafa ALTAŞ, Ali Ulvi UCA, Turan AKDAĞ, Faruk Ömer ODABAŞ, Osman Serhat TOKGÖZ
Jazyk:	angličtina
Rok vydání:	2022
Předmět:	Multiple Sclerosis Irisin Nesfatin-1 Inflammation Apoptosis Oxidative Stress Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571
Zdroj:	Arquivos de Neuro-Psiquiatria (2022)
Druh dokumentu:	article
ISSN:	1678-4227 0004-282x
DOI:	10.1590/0004-282x-anp-2020-0520
Popis:	ABSTRACT Background: Multiple sclerosis (MS) is an inflammatory and neurodegenerative autoimmune chronic neurological disease. Currently, there are no effective serum biomarkers to verify MS diagnosis, to assess disease prognosis, and evaluate response to MS treatment. Objective: The present study is a preliminary assessment of irisin and nesfatin-1 serum levels in patients with relapsing- remitting MS (RRMS). Methods: A total of 86 participants, 42 patients with RRMS diagnosis and 44 healthy controls were included in the study. The serum irisin and nesfatin-1 parameters of the patients and control group members were analyzed. Results: Irisin and nesfatin-1 levels of the RRMS patients were significantly lower than the controls (z: -3.82, p
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/9cc6b9fa661c420d90b9e8501bb0ea05 Zobrazit plný text záznamu View record in DOAJ