First description of basaloid carcinoma of the canine mammary gland: case report

Autor: K.Y.R. Nakagaki, A.B.B. Gonçalves, R.M. Rocha, G.D. Cassali
Jazyk: English<br />Portuguese
Předmět:
Zdroj: Arquivo Brasileiro de Medicina Veterinária e Zootecnia, Vol 71, Iss 3, Pp 878-882
Druh dokumentu: article
ISSN: 1678-4162
DOI: 10.1590/1678-4162-10372
Popis: ABSTRACT The objective of this case report was to describe histopathological and immunohistochemical characteristics of the first reported basaloid carcinomas in the canine mammary gland. Two bitches were treated for tumors in the mammary gland and underwent mastectomy. Microscopic evaluation of these tumors revealed epithelial cells arranged in a predominantly solid pattern with hyperchromatic peripheral cells arranged in a palisade pattern. Metastases in regional lymph nodes were found in both animals, and one bitch exhibited pulmonary metastasis. Immunohistochemistry revealed positive labeling for the basal cell markers cytokeratin 14 and p63. Histopathological and immunohistochemical findings led to diagnoses of basaloid carcinoma of the canine mammary gland with regional and distant metastasis.
Databáze: Directory of Open Access Journals