Activation of viral defense signaling in cancer
| Autor: | Maria Gonzalez-Cao, Niki Karachaliou, Mariacarmela Santarpia, Santiago Viteri, Andreas Meyerhans, Rafael Rosell |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: | |
| Zdroj: | Therapeutic Advances in Medical Oncology, Vol 10 (2018) |
| Druh dokumentu: | article |
| ISSN: | 1758-8359 17588359 |
| DOI: | 10.1177/1758835918793105 |
| Popis: | A coordinated action of innate and adaptive immune responses is required to efficiently combat a microbial infection. It has now become clear that cancer therapies also largely benefit when both arms of the immune response are engaged. In this review, we will briefly describe the current knowledge of innate immunity and how this can be utilized to prime tumors for a better response to immune checkpoint inhibitors. Comments on compounds in development and ongoing clinical trials will be provided. |
| Databáze: | Directory of Open Access Journals |
| Externí odkaz: |
|