Rare cases of primarily infected kidney graft transplantation with the development of purulent complications

Autor: N. V. Shmarina, K. E. Lazareva, I. V. Dmitriev, A. G. Balkarov, D. V. Lonshakov, N. S. Zhuravel, V. V. Smirnova
Jazyk: English<br />Russian
Rok vydání: 2024
Předmět:
Zdroj: Трансплантология (Москва), Vol 16, Iss 3, Pp 353-363 (2024)
Druh dokumentu: article
ISSN: 2074-0506
2542-0909
94524335
DOI: 10.23873/2074-0506-2024-16-3-353-363
Popis: Background. Unexpected transmission of an infectious disease agent with a kidney graft to a recipient is a rare event but it is associated with significant morbidity and mortality, especially when exposed to multidrug-resistant bacteria that have not been eliminated by standard antibiotic prophylaxis.Objective. To demonstrate the need for immediate removal of a primary infected kidney graft in the event of local purulent complications due to the rapid development of sepsis in immunocompromised patients.Results. The paper describes a clinical course of the infectious process in two kidney recipients each of whom underwent transplantation of a primary infected graft from a single donor, taking into consideration the transplantectomy timing and the treatment outcomes.Conclusion. The Case Report shows the need for immediate transplantectomy in a kidney graft recipient when local purulent complications are detected with confirmed primary infection of the graft due to a high risk of the rapid development of sepsis and threat to life.
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