Mycoplasma genitalium adhesin P110 binds sialic-acid human receptors

Autor: David Aparicio, Sergi Torres-Puig, Mercè Ratera, Enrique Querol, Jaume Piñol, Oscar Q. Pich, Ignacio Fita
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-018-06963-y
Popis: How the Mycoplasma genitalium cytadhesins P140 and P110 promote host cell invasion remains poorly understood. Here, combining structural analysis with functional assays, Aparicio et al. identify the P110 domain that binds to sialylated receptors essential for mycoplasma cytadherence.
Databáze: Directory of Open Access Journals