Vitamin D and preeclampsia: A systematic review and meta-analysis
| Autor: | Abdulla AlSubai, Muhammad Hadi Baqai, Hifza Agha, Neha Shankarlal, Syed Sarmad Javaid, Eshika Kumari Jesrani, Shalni Golani, Abdullah Akram, Faiza Qureshi, Shaheer Ahmed, Simran Saran |
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| Jazyk: | angličtina |
| Rok vydání: | 2023 |
| Předmět: | |
| Zdroj: | SAGE Open Medicine, Vol 11 (2023) |
| Druh dokumentu: | article |
| ISSN: | 2050-3121 20503121 |
| DOI: | 10.1177/20503121231212093 |
| Popis: | Objectives: Preeclampsia is one of the most frequent pregnancy disorders, with a global incidence of 2%–8%. Serum 25-hydroxyvitamin D is an essential mineral for human health; some studies suggest link between 25-hydroxyvitamin D deficiency and preeclampsia, while others offer contradictory findings. Thus, the goal of this study is to evaluate the relationships between maternal 25- hydroxyvitamin D concentrations and the risk of preeclampsia. In addition to this, our study also evaluates the effects of 25- hydroxyvitamin D supplementation on the incidence of preeclampsia. Therefore, assessing 25- hydroxyvitamin D’s potential as a possible intervention to lower the risk of preeclampsia. Methods: The Medline database was queried from inception until July 2021 for randomized controlled trials and observational studies without any restrictions. The studies assessing the association between 25-hydroxyvitamin D deficiency and preeclampsia and the impact of 25-hydroxyvitamin D supplementation on the incidence of preeclampsia were incorporated. The results were reported using a random-effects meta-analysis and the Mantel-Haenszel odds ratio. A p -value of |
| Databáze: | Directory of Open Access Journals |
| Externí odkaz: |
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