| Autor: |
Balázs Dezsényi, Zsolt Dubóczki, Tamás Strausz, Eszter Csulak, Veronika Czoma, Zsolt Káposztás, Mária Fehérvári, Áron Somorácz, András Csilek, Attila Oláh, Kálmán Almási, Attila Patonai, Dénes Görög, Zoltán Széll, Zoltán Tolnai, Tamás Sréter, József Danka, Herbert Auer, Beate Grüner, Thomas F. E. Barth, Adriano Casulli |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Předmět: |
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| Zdroj: |
BMC Infectious Diseases, Vol 21, Iss 1, Pp 1-15 (2021) |
| Druh dokumentu: |
article |
| ISSN: |
1471-2334 |
| DOI: |
10.1186/s12879-021-05859-5 |
| Popis: |
Abstract Background Human alveolar echinococcosis (AE) caused by Echinococcus multilocularis is an underreported, often misdiagnosed and mistreated parasitic disease mainly due to its low incidence. The aim of this study was to describe the epidemiological and clinical characteristics of human AE patients in Hungary for the first time. Method Between 2003 and 2018, epidemiological and clinical data of suspected AE patients were collected retrospectively from health database management systems. Results This case series included a total of 16 AE patients. The mean age of patients was 53 years (range: 24–78 years). The sex ratio was 1:1. Four patients (25%) revealed no recurrence after radical surgery and adjuvant albendazole (ABZ) therapy. For five patients (31.3%) with unresectable lesions, a stabilization of lesions with ABZ treatment was achieved. In seven patients (43.8%), progression of AE was documented. The mean diagnostic delay was 33 months (range: 1–122 months). Three AE related deaths (fatality rate 18.8%) were recorded. Conclusions AE is an emerging infectious disease in Hungary with a high fatality rate since based on our results, almost every fifth AE patient died in the study period. Differential diagnosis and appropriate surgical and medical therapy for AE is an urging challenge for clinicians in Hungary, as well as in some other European countries where E. multilocularis is prevalent. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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