| Autor: |
Mame Cheikh Seck, Moustapha Mbow, Sidy Mohamed Seck, Yacine Ameth Dia, Ibrahima Diallo, Marouba Cisse, Moctar Gningue, Victoria Daou, Baratou Coundoul, Yaya Kane, Mouhamadou Moustapha Cisse, Adama Kama, Khadim Diongue, Papa Aly Thiam Gueye, Cheikh Faye, Mamadou Alpha Diallo, Mouhamadou Ndiaye, Aida Sadikh Badiane, Alioune Dièye, Souleymane Mboup, Daouda Ndiaye |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
|
| Zdroj: |
Parasitologia, Vol 3, Iss 2, Pp 142-150 (2023) |
| Druh dokumentu: |
article |
| ISSN: |
2673-6772 |
| DOI: |
10.3390/parasitologia3020015 |
| Popis: |
Toxoplasmosis in immunocompromised patients results in either reactivation of latent toxoplasmosis or acute infection. In the framework of the kidney transplantation program in Senegal, the serological screening of potential pre-transplant and transplanted patients can prevent the disease. This study aimed to assess the seroprevalence of toxoplasmosis in a cohort of hemodialysis patients, candidates for kidney transplantation. To this end, a multicentre cross-sectional study was conducted in 2020 in six dialysis units from five regions. Blood samples and sociodemographic data were collected from each patient. IgG and IgM against T. gondii antibodies were assessed by a chemiluminescent method using Architect ci4100, and statistical analysis was performed using R software. Overall, 211 hemodialysis patients aged from 18 to 77 years were enrolled. The mean age was 42.62 years ± 13.6, and the sex ratio M/F was 1.24. The overall seroprevalence of T. gondii was 41.7%, with the highest value being recorded in the region of Kaolack (44.4%). Patients aged over 60 years were more typically infected, at a proportion of 56.0%. Regarding sex, males elicited a higher prevalence (44.4.%) than females did. Patients of an upper socioeconomic status were less affected, and contact with cats was not associated with toxoplasmosis. By education level, the illiterate group was most affected one. Overall, this first study of toxoplasmosis among Senegalese hemodialysis patients indicates high seroprevalence. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
|
|
Nepřihlášeným uživatelům se plný text nezobrazuje |
K zobrazení výsledku je třeba se přihlásit.
|
