Defining molecular glues with a dual-nanobody cannabidiol sensor

Autor: Shiyun Cao, Shoukai Kang, Haibin Mao, Jiayu Yao, Liangcai Gu, Ning Zheng
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-022-28507-1
Popis: Molecular glue has been used as a broad term describing a class of protein interaction-promoting compounds. Here, the authors outline two unifying thermodynamic features to formally define molecular glues and guide their prospective discovery.
Databáze: Directory of Open Access Journals