Common Findings in Endoscopic Gastric Biopsies in Southeastern Anatolia: Effects of Eating Habits and Helicobacter Pylori Infection

Autor: Burçin Pehlivanoğlu, Bilge Aydın Türk, Serap İşler, Zülfükar Bilge
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: İstanbul Medical Journal, Vol 22, Iss 1, Pp 50-54 (2021)
Druh dokumentu: article
ISSN: 2619-9793
2148-094X
DOI: 10.4274/imj.galenos.2020.74050
Popis: Introduction:Roasted and spicy food (mainly hot pepper) consumption is very common in Southeastern Anatolia. Smoked and spicy diets and Helicobacter pylori (H. pylori) infection are known risk factors for gastric cancer. The aim of this study was to investigate the effects of eating habits on the gastric mucosa, to investigate the rate of H. pylori positivity, and to examine the association of these factors with histopathological features in this region.Methods:Histopathological findings in endoscopic biopsies of 943 consecutive patients were retrospectively evaluated.Results:More than half of the patients were female (54%; n=505), and the median age was 47±17.27 (range: 18-96). The most common non-gastritis histopathologic diagnosis was gastric carcinoma (2.5%; n=24), followed by polypoid lesions (1.6%; n=16). The vast majority of patients (92%) had chronic gastritis, and neutrophilic activity was present in 61% (n=537). The frequencies of atrophy, intestinal metaplasia, and regenerative mucosal changes were significantly correlated with the severity of neutrophilic activity (p
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