DNA repair synthesis and histone deposition partner during homologous recombination

Autor: Amira Elbakry, Szilvia Juhász, Arthur Mathes, Markus Löbrich
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: Molecular & Cellular Oncology, Vol 5, Iss 5 (2018)
Druh dokumentu: article
ISSN: 2372-3556
23723556
DOI: 10.1080/23723556.2018.1511210
Popis: Chromatin remodeling is critical for the regulation of the DNA damage response. We highlight findings from our recent study showing that the deposition of the histone variant H3.3 by the alpha-thalassemia mental retardation X-linked protein (ATRX) and the death domain associated protein (DAXX) chromatin remodeling complex regulates DNA repair synthesis during homologous recombination.
Databáze: Directory of Open Access Journals
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