HIV-1 protease inhibitory substances from the rhizomes of Boesenbergia pandurata Holtt.

Autor: Tassanee Panphadung, Jindaporn Puripattanavong, Sanan Subhadhirasakul, Supinya Tewtrakul
Jazyk: angličtina
Rok vydání: 2003
Předmět:
Zdroj: Songklanakarin Journal of Science and Technology (SJST), Vol 25, Iss 4, Pp 503-508 (2003)
Druh dokumentu: article
ISSN: 0125-3395
Popis: Four flavonoids (pinostrobin, pinocembrin, cardamonin and alpinetin) isolated from the ethanol extract of Boesenbergia pandurata Holtt. (yellow rhizome) were tested for their activities against HIV-1 protease (HIV-PR). The result showed that cardamonin exhibited an appreciable anti-HIV-1 PR activity with an IC50 value of 31 μg/ml.
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