| Autor: |
Ying Chen, Liyong Huang, Huiyong Zhang, Haiyan Sun, Wenke Zhou |
| Jazyk: |
angličtina |
| Rok vydání: |
2016 |
| Předmět: |
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| Zdroj: |
Journal of Functional Foods, Vol 23, Iss , Pp 115-123 (2016) |
| Druh dokumentu: |
article |
| ISSN: |
1756-4646 |
| DOI: |
10.1016/j.jff.2016.02.035 |
| Popis: |
(-)-Epigallocatechin-3-gallate (EGCG) is well known for its beneficial health effects in the treatment of central nervous system (CNS) diseases. Here, the neuro-protective effects of EGCG and their potential mechanisms after subarachnoid haemorrhage (SAH) were investigated. Oxyhaemoglobin (OxyHb)-induced cell growth was accompanied with mitochondrial dysfunction, such as mitochondrial membrane depolarisation, excessive opened mitochondrial membrane permeability transition pore (mPTP), and high relative oxygen species (ROS) level. However, EGCG dose-dependently inhibited cell growth after SAH, especially at 50 µM (p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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Full Text from ScienceDirect