Low Serum Paraoxonase-1 Lactonase and Arylesterase Activities in Obese Children and Adolescents

Autor: Sandor Raluca, Leucuta Daniel, Dronca Eleonora, Niculae Alexandru, Cret Victoria, Silaghi Ciprian, Suciu Soimita
Jazyk: angličtina
Rok vydání: 2015
Předmět:
Zdroj: Romanian Journal of Laboratory Medicine, Vol 23, Iss 4, Pp 385-396 (2015)
Druh dokumentu: article
ISSN: 2284-5623
DOI: 10.1515/rrlm-2015-0038
Popis: Serum paraoxonase-1 (PON1) binds mainly to high density lipoproteins (HDLs) and protects low density lipoproteins (LDLs) against oxidation. While paraoxonase and arylesterase activities are traditionally assayed, lactonase activity, accounting for protection against LDL oxidation, was less investigated in obese children and adolescents. Therefore, we aimed to measure lactonase, paraoxonase and arylesterase activities, oxidized LDL (ox-LDL) and malondialdehyde (MDA) levels in obese children and adolescents.
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