A fast and highly efficient one-pot synthesis of novel isoxazolyl pyrido[2,3-b][1,4]oxazin-2(3H)-ones via Smiles rearrangement using task-specific ionic liquid [HMIm]BF4 as green solvent
Autor: | Modugu Nagi Reddy, Pittala Praveen Kumar, Eligeti Rajanarendar |
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Jazyk: | angličtina |
Rok vydání: | 2017 |
Předmět: | |
Zdroj: | Green Chemistry Letters and Reviews, Vol 10, Iss 1, Pp 48-53 (2017) |
Druh dokumentu: | article |
ISSN: | 1751-8253 1751-7192 17518253 |
DOI: | 10.1080/17518253.2017.1285966 |
Popis: | A facile and convenient procedure for the synthesis of isoxazolyl pyrido[2,3-b][1,4]oxazin-2(3H)-ones via Smiles rearrangement from isoxazole amine, chloroacetyl chloride and 2-chloro-3-hydroxypyridine using [HMIm]BF4 as task-specific ionic liquid has been described. The protocol proves to be efficient and environmentally benign in terms of high yields, eco-friendly solvent, ease of recovery, and reusability of reaction medium. |
Databáze: | Directory of Open Access Journals |
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