Bos taurus–indicus hybridization correlates with intralocus sexual-conflict effects of PRDM9 on male and female fertility in Holstein cattle

Autor:	Eyal Seroussi, Andrey Shirak, Moran Gershoni, Ephraim Ezra, Daniel Jordan de Abreu Santos, Li Ma, George E. Liu
Jazyk:	angličtina
Rok vydání:	2019
Předmět:	Genomic conflict Recombination Dairy Beef Fertility Holstein Genetics QH426-470
Zdroj:	BMC Genetics, Vol 20, Iss 1, Pp 1-11 (2019)
Druh dokumentu:	article
ISSN:	1471-2156
DOI:	10.1186/s12863-019-0773-5
Popis:	Abstract Background Crossover localization during meiotic recombination is mediated by the fast-evolving zinc-finger (ZnF) domain of gene PRDM9. To study its impact on dairy cattle performance, we compared its genetic variation between the relatively small Israeli (IL) Holsteins and the North American (US) Holsteins that count millions. Results Initially, we analyzed the major BTA1 haplotypes present in IL Holsteins based on the 10 most telomeric SNPs of the BovineSNP50 BeadChip. Sequencing of representative haplotype carriers indicated that for all frequent haplotypes (> 6%), the variable PRDM9 ZnF array consisted of seven tandem ZnF repeats. Two rare haplotypes (frequency
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/9c4946818fd94fbe8d996dffaecbc689 Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF Plný text ve formátu HTML
Nepřihlášeným uživatelům se plný text nezobrazuje	K zobrazení výsledku je třeba se přihlásit.