HIV Infection and Osteoarticular Tuberculosis: Strange Bedfellows
| Autor: | B. Hodkinson, N. Osman, S. Botha-Scheepers |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: | |
| Zdroj: | Case Reports in Rheumatology, Vol 2016 (2016) |
| Druh dokumentu: | article |
| ISSN: | 2090-6889 2090-6897 |
| DOI: | 10.1155/2016/5718423 |
| Popis: | We report the case of a 47-year-old female patient with rheumatoid arthritis and HIV infection presenting with a 3-week history of a painful swollen knee, increased serum inflammatory markers, and a low CD4 lymphocyte count. The diagnosis of TB arthritis was made by synovial fluid culture, GeneXpert/PCR, and confirmed by histopathology of a synovial biopsy. A mini literature review suggests that although HIV infection is associated with extrapulmonary TB, osteoarticular TB is a relatively unusual presentation in an HIV positive patient. The diagnostic utility of the GeneXpert test is explored. We also describe the patient’s good response to an intra-articular corticosteroid injection in combination with standard anti-TB therapy. |
| Databáze: | Directory of Open Access Journals |
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