One-Step Preparation of Adhesive Composite Hydrogels through Fast and Simultaneous In Situ Formation of Silver Nanoparticles and Crosslinking

Autor: Yi Li, Yunchao Xiao, Man Xi, Guibin Li, Yang Jiang
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Gels, Vol 8, Iss 5, p 256 (2022)
Druh dokumentu: article
ISSN: 2310-2861
DOI: 10.3390/gels8050256
Popis: In this study, a series of gelatin/silver nanoparticles (AgNPs) composite hydrogels are prepared for the first time through the facile in situ formation of AgNPs. AgNPs, which are formed by reducing Ag+ using dopamine-conjugated gelatins. These can simultaneously crosslink gelatin molecules, thus generating three-dimentional and porous hydrogels. The gelation time and pore sizes of these composite hydrogels can be controlled by controlling the feeding concentration of AgNO3 and weight content of gelatin in water, respectively. The feeding concentration of AgNO3 also has an effect on the equilibrium swelling ratio of the hydrogels. Moreover, these composite hydrogels, with a controllable gelation time and in situ forming ability, exhibit good adhesive properties and can be used as drug-release depots.
Databáze: Directory of Open Access Journals