Factors associated with adherence to antiretroviral therapy among HIV-infected children in Pokhara, Nepal: a cross-sectional study

Autor: Ramchandra Bastola, Bhawana Sigdel, Krishna Subedi, Sunita Ghimire, Amrita Ghimire
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: HIV & AIDS Review. International Journal of HIV-Related Problems, Vol 23, Iss 1, Pp 66-71 (2024)
Druh dokumentu: article
ISSN: 1730-1270
1732-2707
DOI: 10.5114/hivar.2024.135826
Popis: Introduction Children below the age of 15 years account for the majority of acquired immunodeficiency syndrome (AIDS)-related deaths in Nepal. Antiretroviral therapy (ART) improves health and prolongs lives of people with human immunodeficiency virus (HIV). Poor adherence to ART provides clue to a sub-therapeutic level of antiretroviral drug, which can facilitate multi-drug resistance of similar regimen, leading to treatment failure and death. The objective of this study was to determine the level of adherence to ART and its associated factors among HIV-infected children aged 0-14 years in Pokhara Academy of Health Sciences (PoAHS), Pokhara, Nepal. Material and methods This cross-sectional study was conducted between September 15th, 2020 and February 15th, 2021, and included 57 HIV-infected children. Caregivers of the children were questioned with a pre-tested, semi-structured questionnaire, which was later translated verbally to Nepali. Trained doctors took the interviews. Acquired data was entered using SPSS version 17 software for analysis. Level of significance was set at p
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