The Effect of the Bujeonghangam-tang Extract on Hepatocellular Carcinogenesis and Hepatic Cirrhosis Induced by Diethylnitrosamine and CCl4 in Rats
| Autor: | Young-Ho Moon, Jin-Hee Won, Goo Moon, Rae-Kyong Heo, Kee-Moon Seung, In-Young Lee, Myung-Joon Jang, So-Yeon Kwon, Deok-Seon Yu |
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| Jazyk: | English<br />Korean |
| Rok vydání: | 2010 |
| Předmět: | |
| Zdroj: | Journal of Pharmacopuncture, Vol 13, Iss 2, Pp 13-31 (2010) |
| Druh dokumentu: | article |
| ISSN: | 2093-6966 2234-6856 |
| DOI: | 10.3831/KPI.2010.13.2.013 |
| Popis: | Objective : Bujeonghangam-tang(BH) has been used for cure of tumor as a traditional medicine. This study was carried out to clarify the effect of BH extract on hepatocellular carcinogenesis and hepatic cirrhosis induced by Diethylnitrosamine(DENA) and CCl4 in Rats. Method : Experimental groups were divided into two, 8th and 12th week groups, and subdivided into four; normal group(Nor), cirrhosis and hepatic cancer inducing control group(Con), and BH extract 320 ㎎/㎏/day(BHA) or 640 ㎎/㎏/day(BHB) administered groups to Con. Result : In the 8th week group: The body weight decreased significantly in Con compared with the Nor. The activities of transaminase, alkaline phosphatase(ALP), and lactacte dehydrogenase(LDH) were significantly increased(p |
| Databáze: | Directory of Open Access Journals |
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