IMPACT OF MULTIPLE LIFESTYLE INTERVENTIONS ON METABOLIC HEALTH AND REMISSION OF PREDIABETES AND TYPE 2 DIABETES: A TWO-YEAR CLINICAL EXPERIENCE

Autor: Josep Iglesies-Grau, Valérie Dionne, Élise Latour, Karine Lamoureux, Véronique Pelletier, Marc Bisaillon, Geneviève Tessier, Johanne Bertholet, Valérie Guilbeault, Annie Berthiaume, Lise Aubut, Nacima Hamrioui, Marie-Hélène Morissette, Christine Gagnon, François Simard, Anil Nigam, Philippe L. L'Allier, Louis Bherer, Nadia Bouabdallaoui, Martin Juneau
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: American Journal of Preventive Cardiology, Vol 13, Iss , Pp 100397- (2023)
Druh dokumentu: article
ISSN: 2666-6677
DOI: 10.1016/j.ajpc.2022.100397
Popis: Therapeutic Area: Diabetes, Lifestyle Interventions Background: Different intensive lifestyle interventions have been shown to be useful for effective control and even reversal of prediabetes and type 2 diabetes (T2D). Methods: The Montreal Heart Institute Cardiovascular Prevention Center (EPIC) started a comprehensive lifestyle clinic to study the impact of 6 and 12-month non-pharmacological interventions on metabolic health and remission of these two conditions.Between January 2019 and December 2020, 81 prediabetic (HbA1c ≥ 5.7%) and 184 T2D (HbA1c ≥ 6.5%) were recruited. All participants received regular nutritional counselling (therapeutic moderate carbohydrate restriction Mediterranean diet) and personalized physical exercise prescription (≥30 minutes of moderate aerobic training, 5 times a week, and strength training). Anthropometric measures and fasting blood analysis were measured at 0, 3, 6 and 12 months. Glucose-lowering therapies were not modified, unless necessary.Complete remission of prediabetes and T2D was defined as HbA1c
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