Optimal timing for the first cystoscopic follow-up using time-to-treatment initiation analysis of oncologic outcomes in primary non-muscle invasive bladder cancer

Autor:	Jeong-Soo Kim, Jooyoung Lee, Tuan Thanh Nguyen, Se Young Choi
Jazyk:	angličtina
Rok vydání:	2024
Předmět:	Cystoscopy Follow-up Non-muscle invasive bladder cancer Restricted cubic spline function Time to treatment initiation Medicine Science
Zdroj:	Scientific Reports, Vol 14, Iss 1, Pp 1-8 (2024)
Druh dokumentu:	article
ISSN:	2045-2322
DOI:	10.1038/s41598-024-58809-x
Popis:	Abstract Various guidelines recommend the first follow-up cystoscopy at 3 months; however, no data exist on the optimal timing for initial follow-up cystoscopy. We tried to provide evidence on the timing of the first cystoscopy after the initial transurethral resection of bladder tumor (TUR-BT) for patients with non-muscle invasive bladder cancer (NMIBC) using big data. This was a retrospective National Health Insurance Service database analysis. The following outcomes were considered: recurrence, progression, cancer-specific mortality, and all-cause mortality. Exposure was the time-to-treatment initiation (TTI), a continuous variable representing the time to the first cystoscopy from the first TUR-BT within 1 year. Additionally, we categorized TTI (TTIc) into five levels:
Databáze:	Directory of Open Access Journals
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