Total Hepatitis B Core Antigen Antibody, a Quantitative Non-Invasive Marker of Hepatitis B Virus Induced Liver Disease.

Autor: Quan Yuan, Liu-Wei Song, Daniela Cavallone, Francesco Moriconi, Beatrice Cherubini, Piero Colombatto, Filippo Oliveri, Barbara Agata Coco, Gabriele Ricco, Ferruccio Bonino, James Wai Kuo Shih, Ning-Shao Xia, Maurizia Rossana Brunetto
Jazyk: angličtina
Rok vydání: 2015
Předmět:
Zdroj: PLoS ONE, Vol 10, Iss 6, p e0130209 (2015)
Druh dokumentu: article
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0130209
Popis: Non invasive immunologic markers of virus-induced liver disease are unmet needs. We tested the clinical significance of quantitative total and IgM-anti-HBc in well characterized chronic-HBsAg-carriers. Sera (212) were obtained from 111 HBsAg-carriers followed-up for 52 months (28-216) during different phases of chronic-HBV-genotype-D-infection: 10 HBeAg-positive, 25 inactive-carriers (HBV-DNA≤2000IU/ml, ALT
Databáze: Directory of Open Access Journals