Early outcomes after pulmonary endarterectomy for chronic thromboembolic pulmonary hypertension in the era of epoprostenol sodium
| Autor: | Yusuke Sakurai, Yoshiyuki Takami, Akihiro Kobayashi, Tsutomu Yanagisawa, Kentaro Amano, Yoshiro Higuchi, Masato Tochii, Michiko Ishida, Toshimitsu Satou, Hiroshi Ishikawa, Masayoshi Kobayashi, Koji Hattori, Motomi Ando, Yasushi Takagi |
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| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: | |
| Zdroj: | Fujita Medical Journal, Vol 3, Iss 3, Pp 62-66 (2017) |
| Druh dokumentu: | article |
| ISSN: | 2189-7247 2189-7255 |
| DOI: | 10.20407/fmj.3.3_62 |
| Popis: | Objectives: Pulmonary endarterectomy (PEA) for chronic thromboembolic pulmonary hypertension (CTEPH) is technically demanding. We reviewed the surgical outcomes of consecutive patients who underwent PEA with aggressive use of pulmonary vasodilators, including epoprostenol sodium. Methods: We retrospectively assessed perioperative clinical data of 122 patients with CTEPH who underwent PEA with hypothermic circulatory arrest between 2005 and 2013. Peri-operatively, all of the patients received pulmonary vasodilator therapy, including epoprostenol sodium and beraprost sodium. Results: Patients were classified as having CTEPH type 1 (n=57), type 2 (n=32), and type 3 (n=33) disease according to the Jamison classification system. In-hospital mortality was 7.4% (n=9), caused by right heart failure (n=5), pulmonary hemorrhage (n=3), and pneumonia (n=1). The 113 patients who survived PEA showed significantly decreased mPAP (46±11 to 23±10 mmHg, P |
| Databáze: | Directory of Open Access Journals |
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