Atypical carcinoid and large cell neuroendocrine carcinoma of the lung: a proteomic dataset from formalin-fixed archival samples

Autor: Alessandro Tanca, Maria Filippa Addis, Salvatore Pisanu, Marcello Abbondio, Daniela Pagnozzi, Albino Eccher, Guido Rindi, Paolo Cossu-Rocca, Sergio Uzzau, Giuseppe Fanciulli
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: Data in Brief, Vol 7, Iss , Pp 529-531 (2016)
Druh dokumentu: article
ISSN: 2352-3409
DOI: 10.1016/j.dib.2016.02.083
Popis: Here we present a dataset generated using formalin-fixed paraffin-embedded archival samples from two rare lung neuroendocrine tumor subtypes (namely, two atypical carcinoids, ACs, and two large-cell neuroendocrine carcinomas, LCNECs). Samples were subjected to a shotgun proteomics pipeline, comprising full-length protein extraction, SDS removal through spin columns, in solution trypsin digestion, long gradient liquid chromatography peptide separation and LTQ-Orbitrap mass spectrometry analysis. A total of 1260 and 2436 proteins were identified in the AC and LCNEC samples, respectively, with FDR
Databáze: Directory of Open Access Journals