Genotype identification of Enterocytozoon bieneusi isolates from stool samples of HIV-infected Tunisian patients

Autor: Chabchoub N., Abdelmalek R., Breton J., Kanoun F., Thellier M., Bouratbine A., Aoun K.
Jazyk: angličtina
Rok vydání: 2012
Předmět:
Zdroj: Parasite, Vol 19, Iss 2, Pp 147-151 (2012)
Druh dokumentu: article
ISSN: 1252-607X
1776-1042
DOI: 10.1051/parasite/2012192147
Popis: The microsporidian species Enterocytozoon bieneusi is a major cause of chronic diarrhea and malabsorption in patients with AIDS. Genotyping was performed on seven E. bieneusi strains for the first time in Tunisia. All the strains were isolated from stool samples of humans with immunodeficiency virus (HIV) infection. Analysis of the ribosomal RNA gene internal transcribed spacer (rDNA ITS) allowed the identification of three distinct genotypes previously described in other studies. Genotypes D and B were characterized in four and two respectively. The Peruvian genotype (Peru 8) was detected in the last isolate. These results indicate a genetic diversity in E. bieneusi strains from HIV Tunisian patients and suggest the coexistence of both zoonotic and anthroponotic route of transmission.
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