| Autor: |
Mostafa Qorbani, Motahar Heidari-Beni, Hanieh-Sadat Ejtahed, Gita Shafiee, Farid Goodarzi, Seyed Saeed Tamehri Zadeh, Majid Khademian, Nami Mohammadian Khonsari, Mohammad Esmaeil Motlagh, Hamid Asayesh, Mohammad Jabbari, Ramin Heshmat, Mehdi Ebrahimi, Roya Kelishadi |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Předmět: |
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| Zdroj: |
BMC Nutrition, Vol 7, Iss 1, Pp 1-8 (2021) |
| Druh dokumentu: |
article |
| ISSN: |
2055-0928 |
| DOI: |
10.1186/s40795-021-00477-5 |
| Popis: |
Abstract Background Metabolic syndrome (MetS) starts from early life and is one of the important underlying factors for non-communicable diseases (NCDs) in adulthood. Controversial evidence exists on the role of vitamin D deficiency in increasing the risk of pediatric MetS. Objective This study aimed to assess the relationship between vitamin D level with MetS and its components in children and adolescents. Methods This nationwide cross-sectional study was performed as part of a surveillance program in Iran. Participants were 2596 students, aged 7 to 18 years, living in 30 provinces. In addition to filling questionnaires, a physical examination was conducted, and blood samples were collected. The serum concentration of 25-hydroxy vitamin D (25(OH)D) was measured using the direct competitive immunoassay chemiluminescence method. Results 2596 students with a mean age of 12.2 y (55.1% boys) were recruited. Prevalence of vitamin D deficiency and insufficiency in participants was 10.6% (n = 276), and 60.5% (n = 1570), respectively. The prevalence of MetS was higher in the vitamin D deficient group. Students with deficient vitamin D levels had higher odds of MetS (OR: 4.25, 95%CI: 2.26–7.98), abdominal obesity (OR: 2.24, 95%CI: 1.61–3.12), low HDL-C (OR: 1.65, 95%CI: 1.18–2.30) and high fasting blood sugar (OR: 2.56, 95%CI: 1.43–4.57) in comparison to those with sufficient level of vitamin D. Conclusion Vitamin D deficiency was associated with increased odds of MetS and its components in the Iranian pediatric population. These findings underscore the importance of prevention and control of vitamin D deficiency in preventative programs against NCDs. |
| Databáze: |
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| Externí odkaz: |
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