| Autor: |
Stephanie Gaydos, Anthony Hlavacek, Susan Evenhouse, Jacob Strelow, Shahryar Chowdhury, Lanier Jackson |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
|
| Zdroj: |
International Journal of Cardiology Congenital Heart Disease, Vol 13, Iss , Pp 100408- (2023) |
| Druh dokumentu: |
article |
| ISSN: |
2666-6685 |
| DOI: |
10.1016/j.ijcchd.2022.100408 |
| Popis: |
Patients with repaired Tetralogy of Fallot (rTOF) have risks of late life-threatening sequelae, including right ventricular (RV) dilation and failure, arrhythmias, and sudden death. QRS prolongation is a well-known ECG predictor of these outcomes but has poor sensitivity for mortality. Growing evidence demonstrates QRS fragmentation (fQRS) as a better prognostic marker for mortality in adults with rTOF, though the two markers have not been directly compared as correlates for CMR abnormalities. Additionally, fQRS has never been studied in pediatric TOF. This single institution retrospectively reviewed 138 CMRs in rTOF patients (median age 21.7 years) who had a corresponding 12-lead ECG within 1 year. fQRS was defined as ≥3 R-waves/notches in the R/S complex (>2 in right bundle branch block) in ≥2 contiguous leads. QRS prolongation was defined as QRS ≥160 ms. Nearly half (46%) the sample had fQRS (42.1% of pediatric subgroup), and 26% had QRS prolongation. Both markers were significantly associated with reduced RV ejection fraction (EF%) (p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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