| Autor: |
Atanu Maiti, Adam K. Hedger, Wazo Myint, Vanivilasini Balachandran, Jonathan K. Watts, Celia A. Schiffer, Hiroshi Matsuo |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022) |
| Druh dokumentu: |
article |
| ISSN: |
2041-1723 |
| DOI: |
10.1038/s41467-022-34752-1 |
| Popis: |
Here, the enzymatic activity of APOBEC3G resulting in conversion of 2′-deoxy-zebularine into a hydration product allowed the authors to capture the transition state, which provides a blueprint for designing a new class of transition state-mimicking inhibitors for this class of enzyme. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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