Total Th1/Th2 cytokines profile from peripheral blood lymphocytes in normal pregnancy and preeclampsia syndrome

Autor:	Iara dos Santos Fagundes, Eduardo Pletsch Brendler, Isadora Nunes Erthal, Raquel Jaqueline Eder Ribeiro, Rafaela Siviero Caron-Lienert, Denise Cantarelli Machado, Bartira Ercília Pinheiro da Costa, Carlos Eduardo Poli-de-Figueiredo
Jazyk:	angličtina
Rok vydání:	2022
Předmět:	pregnancy induced hypertension inflammation flow cytometry interleukins Gynecology and obstetrics RG1-991
Zdroj:	Hypertension in Pregnancy, Vol 41, Iss 1, Pp 15-22 (2022)
Druh dokumentu:	article
ISSN:	1064-1955 1525-6065 10641955
DOI:	10.1080/10641955.2021.2008424
Popis:	To evaluate total Th1/Th2 cytokines in CD3+ cells (immunocompetent T-lymphocytes) and peripheral blood lymphocytes, mostly CD4+ (T helper cells) and CD8+ (T-cytotoxic cells) subpopulations in preeclampsia. Total blood leukocytes and lymphocytes counts, percent cells: CD3+, INF-g+/CD3+, IL-4+/CD3+, and IL-10+/CD3+, CD4+/CD8+ were determined by flow-cytometry. Preeclampsia (n= 26) and normal pregnancy (n= 25) participants were age and gestational age matched. CD4+ lymphocytes count was higher in preeclampsia, compared with normal pregnancy (43.6 ± 5.8 vs 37.6 ± 5.6%; P
Databáze:	Directory of Open Access Journals
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