Sulfonated poly(ether ether ketone)/hydroxyapatite membrane as biomaterials: process evaluation
| Autor: | Cristiane Agra Pimentel, José William de Lima Souza, Flávia Suzany Ferreira dos Santos, Mayelli Dantas de Sá, Valéria Pereira Ferreira, Gislaine Bezerra de Carvalho Barreto, José Filipe Bacalhau Rodrigues, Wladymyr Jefferson Bacalhau de Sousa, Cláudio Orestes Britto Filho, Francisco Kegenaldo Alves de Sousa, Marcus Vinicius Lia Fook |
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| Jazyk: | English<br />Portuguese |
| Rok vydání: | 2019 |
| Předmět: | |
| Zdroj: | Polímeros, Vol 29, Iss 1 (2019) |
| Druh dokumentu: | article |
| ISSN: | 1678-5169 0104-1428 |
| DOI: | 10.1590/0104-1428.01018 |
| Popis: | Abstract Poly(ether ether ketone) (PEEK) has excellent properties, such as high biocompatibility and an elastic modulus similar to bone, which makes it a suitable biomaterial. When modified with sulfuric acid (H2SO4) and hydroxyapatite (HA), its workability and bioactivity is enhanced, and this makes it of great importance in medicine. This study investigates a better combination of process parameters to manufacture sulfonated PEEK/HA (SPEEK/HA) membranes for biomaterials. Chemical, thermal, and biological analyses were carried out on all samples. The sulfonated structure was observed to enhance wettability, adhesion, and cell viability. Furthermore, an increase in the degree of sulfonation facilitated their workability as required for biomaterials; making them suitable for osseointegration. Besides, the SPEEK/HA membranes presented cell adhesion, confirming the viability to use as biomaterial. This study presents a cheap alternative method to easily process biomaterials of improved workability. |
| Databáze: | Directory of Open Access Journals |
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