The potential therapeutic roles of dental pulp stem cells in spinal cord injury

Autor: Jing Fu, Wenjie Li, Tengfei Mao, Zaipeng Chen, Lili Lai, Jiachen Lin, Zhiqiang Nie, Yunkai Sun, Yanqin Chen, Qin Zhang, Xigong Li
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Frontiers in Molecular Biosciences, Vol 11 (2024)
Druh dokumentu: article
ISSN: 2296-889X
DOI: 10.3389/fmolb.2024.1363838
Popis: Spinal cord injury (SCI) can lead to serious functional disorders, which have serious impacts on patients and society. The current traditional treatments of SCI are not effective the injured spinal cord is difficult to repair and regenerate. In recent years, stem cell transplantation for the treatment of SCI has been a hot research topic. Dental pulp stem cells have strong abilities of self-renewal and multi-directional differentiation, and have been applied for tissue engineering and regenerative medicine. And dental pulp stem cells have certain advantages in neuro-regenetation, bringing new hope to biotherapy for SCI. This article reviews the characteristics of dental pulp stem cells and their research progress in the treatment of SCI.
Databáze: Directory of Open Access Journals