RAPID DETECTION OF CARBAPENEMASES AND ESKAPEEc BACTERIA
| Autor: | Okan AYDOGAN, Fatma KOKSAL CAKIRLAR |
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| Jazyk: | English<br />French |
| Rok vydání: | 2021 |
| Předmět: | |
| Zdroj: | Archives of the Balkan Medical Union, Vol 56, Iss 2, Pp 142-149 (2021) |
| Druh dokumentu: | article |
| ISSN: | 1584-9244 2558-815X |
| DOI: | 10.31688/ABMU.2021.56.2.01 |
| Popis: | Introduction. Carbapenems have been the ultimate antibiotics for the treatment of infections caused by multidrug-resistant bacteria. However, recently, carbapenems-resistant bacteria have emerged significantly. The objective of the study was the identification of ESKAPEEc bacteria and rapid detection of carbapenemase production. Materials and methods. We tried a novel rapid test methodology that detects some carbohydrates metabolization associated with bacterial growth in the presence of imipenem. The formation of acid metabolites is evidenced by a color change of a pH indicator. Results. Carbapenemase production is phenotypically demonstrated in carbapenem-resistant bacterial strains. In the study, carbapenemase production was detected within 3 hours, and identification of ESKAPEEc bacteria was completed within 4 hours by carbohydrate metabolism. Conclusions. In conclusion, our cost-effective technique may provide a practical solution for the determination of multi-drug resistance by using the fermentation metabolism in bacteria. |
| Databáze: | Directory of Open Access Journals |
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