Therapeutic effect on pyriform sinus carcinoma resection via paraglottic space approach

Autor: Lei Wang, Dayu Liu, Ruijie Sun, Zhen Jiang, Jianlin Yue
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Frontiers in Surgery, Vol 9 (2023)
Druh dokumentu: article
ISSN: 2296-875X
DOI: 10.3389/fsurg.2022.1068754
Popis: ObjectiveTo analyse the surgical indications, surgical efficacy and key influencing factors of prognosis of using a novel surgical approach for pyriform sinus carcinoma resection utilising the paraglottic space.MethodsFrom 2014 to 2017, 93 patients with squamous cell carcinoma originating in the pyriform sinus were resected through the paraglottic space approach. The postoperative laryngeal function preservation, complications, survival rate and prognostic factors were analysed.ResultsAll patients were followed up for more than 5 years. The 2, 3 and 5 year overall survival rates of the patients were 77.2%, 61.6% and 47.4%, respectively. The univariate analysis of survival rate showed that primary tumour T stage and N stage had a statistically significant effect on the survival rate of patients (P = 0.047 and P
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