| Autor: |
Bing-Chen eLiu, Xiao-Yu eLu, Xiang eSong, Ke-Yu eLei, Abdel A Alli, Hui-Fang eBao, Douglas C Eaton, He-Ping eMa |
| Jazyk: |
angličtina |
| Rok vydání: |
2013 |
| Předmět: |
|
| Zdroj: |
Frontiers in Physiology, Vol 3 (2013) |
| Druh dokumentu: |
article |
| ISSN: |
1664-042X |
| DOI: |
10.3389/fphys.2012.00483 |
| Popis: |
Scanning ion conductance microscope (SICM), which enables high-resolution imaging of cell surface topography, has been developed for over two decades. However, only recently, a unique scanning mode is increasingly used in biological studies to allow SICM to detect the surface of live cells. More recently, in combination with confocal microscopy and patch-clamp electrophysiological techniques, SICM allows investigators to localize proteins or ion channels in a specific nanostructure at the cell surface. This article will briefly review SICM nanotechnique and summarize the role of SICM in biological studies. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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