Evaluation of Tumor Budding in Predicting Survival for Gastric Carcinoma Patients in Vietnam
Autor: | Tu Van Dao MD, PhD, Chu Van Nguyen MD, PhD, Quang Tien Nguyen MD, PhD, Ha Thi Ngoc Vu MD, Huyen Thi Phung MD, PhD, Oanh Thi Bui Pharm, MPH, Dung Khac Nguyen Pharm, PhD, Bang Viet Luong MD, Thuan Van Tran MD, PhD |
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Jazyk: | angličtina |
Rok vydání: | 2020 |
Předmět: | |
Zdroj: | Cancer Control, Vol 27 (2020) |
Druh dokumentu: | article |
ISSN: | 1073-2748 10732748 |
DOI: | 10.1177/1073274820968883 |
Popis: | Background: Tumor budding (Bd) has been demonstrated to be a promising prognostic factor in many carcinomas and in gastric cancer. It may represent an optimal additional parameter that is helpful for risk stratification in gastric adenocarcinoma. Hence, the present research was designed to predict the survival outcomes of gastric cancer in Vietnam, applying the tumor budding criteria of the International Tumor Budding Consensus Conference (ITBCC) 2016. Methods: The present study was conducted on 109 gastric cancer patients who underwent surgery but did not receive neo-adjuvant chemotherapy from 2012 to 2015. The patients’ clinicopathological features were recorded. Bd was evaluated according to the 2016 ITBCC criteria and classified as Bd1 (0–4 buds), Bd2 (5–9 buds), and Bd3 (≥10 buds) grades, in addition to being categorized into 2 main Bd groups: low ( |
Databáze: | Directory of Open Access Journals |
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