| Autor: |
Daisuke Okamura, Akira Matsuda, Maho Ishikawa, Tomoya Maeda, Ken Tanae, Mika Kohri, Naoki Takahashi, Nobutaka Kawai, Norio Asou, Masami Bessho |
| Jazyk: |
angličtina |
| Rok vydání: |
2014 |
| Předmět: |
|
| Zdroj: |
Leukemia Research Reports, Vol 3, Iss 1, Pp 24-27 (2014) |
| Druh dokumentu: |
article |
| ISSN: |
2213-0489 |
| DOI: |
10.1016/j.lrr.2014.03.002 |
| Popis: |
Myelodysplastic syndromes with myelofibrosis (MDS-F) is a poor prognostic hematopoietic disorder. Azacitidine was shown to prolong survival of high-risk MDS patients. However, the effects of azacitidine on MDS-F have yet to be elucidated. Azacitidine was administered to a 74-year-old man with MDS-F at a dose of 75 mg/m2/daily subcutaneously for 7 days every 28 days. Hematologic improvements were observed according to the International Working Group 2006 criteria after 8 cycles of the azacitidine treatment, and complete remission was achieved after 14 cycles. The grade of myelofibrosis was also improved. The therapeutic activity of azacitidine was confirmed in our MDS-F patient. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
|
